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KMID : 0361020110540060419
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Korean Journal of Otolaryngology - Head and Neck Surgery
2011 Volume.54 No. 6 p.419 ~ p.422
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A Case of Postradiation Chondrosarcoma of the Sphenoid and Clivus
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Lim Geun-Hye
Kim Jeong-Kyu
Shin Seung-Heon
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Abstract
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Radiation-induced chondrosarcoma is very rarely encountered in the head and neck malignancy. Rate of chondrosarcoma is 9% of all radiation-induced bone sarcomas. Postradiation chondrosarcoma, like their spontaneous counterparts, are relatively radioresistant tumors, and prompt radical surgery has been the mainstay of therapy. However, not all postradiation chondrosarcoma are amenable to radical surgery. The location of the tumor is one of the most important factors in choosing a therapeutic modality and significantly influences the survival rate. The authors experienced a case of chondrosarcoma of the sphenoid sinus and clivus accompanying sixth and ninth cranial nerve palsies after radiation therapy of nasopharyngeal carcinoma.
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KEYWORD
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Nasopharyngeal carcinoma, Radiation therapy, Chondrosarcoma
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